Listar por autor "Fernández-Bertólez, Natalia"

Mostrando ítems 1-8 de 8

    • Comparative Study of Toxicological Effect of Iron Oxide Nanoparticles in Human Nerve Cells 

      Fernández-Bertólez, Natalia (2018)
      [Abstract] Due to their unique physicochemical properties, iron oxide nanoparticles (ION) have great potential for several biomedical applications, particularly those focused on nervous system. ION surface can be coated ...

    • Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos 

      Valdiglesias, Vanessa; Alba-González, Anabel; Fernández-Bertólez, Natalia; Touzani, Assia; Ramos-Pan, Lucía; Reis, Ana Teresa; Moreda-Piñeiro, Jorge; Yáñez, Julián; Laffon, Blanca; Folgueira, Mónica (MDPI, 2023-08-01)
      [Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ...

    • Estudio de la citotoxicidad de nanopartículas de óxido de hierro en células neuronales humanas mediante citometría de flujo 

      Fernández-Bertólez, Natalia (2015)
      Las propiedades físico-químicas especiales de los nanomateriales (materiales a escala nanométrica), relacionadas con su elevada área superficial y gran reactividad, los hacen útiles para numerosas aplicaciones en muy ...

    • Relationship between DNA damage measured by the comet-assay and cognitive function 

      Lorenzo-López, Laura; Lema-Arranz, Carlota; Fernández-Bertólez, Natalia; Costa, Solange; Costa, Carla; Teixeira, Joao Paulo; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca (Elsevier, 2022-10-17)
      [Abstract] Recent studies exploring the relationship between DNA damage measured by the comet assay (single-cell gel electrophoresis) and cognitive function in both animal models and humans are reviewed and summarized. ...

    • Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage 

      Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Lema-Arranz, Carlota; Rodríguez-Fernández, Raquel; Pásaro, Eduardo; Reis, Ana Teresa; Teixeira, João; Costa, C.; Laffon, Blanca (MDPI, 2021-07-27)
      [Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ...

    • Suitability of Salivary Leucocytes to Assess DNA Repair Ability in Human Biomonitoring Studies by the Challenge-Comet Assay 

      Fernández-Bertólez, Natalia; Lema Arranz, Carlota; Fraga, S.; Teixeira, Joao; Pasaro, Eduardo; Lorenzo-López, Laura; Valdiglesias, Vanessa; Laffon, Blanca (Elsevier, 2022)
      [Abstract] The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood ...

    • Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells 

      Fernández-Bertólez, Natalia; Brandão, Fátima; Costa, C.; Pásaro, Eduardo; Teixeira, João; Laffon, Blanca; Valdiglesias, Vanessa (2021)
      [Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ...

    • Toxoplasma gondii IgG serointensity is positively associated with frailty 

      Mohyuddin, Hira; Laffon, Blanca; Teixeira, Joao P.; Costa, Solange; Teixeira-Gomes, Armanda; Pásaro, Eduardo; Constantine, Niel; Dagdag, Aline; Ortmeyer, Heidi K.; Tizenberg, Boris; Afram, Liubov; Yen, Poyu; Marano, Christopher; Lowry, Christopher A.; Hoisington, Andrew J.; RachBeisel, Jill A.; Valdiglesias, Vanessa; Lema-Arranz, Carlota; Fernández-Bertólez, Natalia; Maseda, Ana; Millán-Calenti, José Carlos; Kovacs, Elizabeth J.; Gostner, Johanna M.; Fuchs, Dietmar; Brenner, Lisa A.; Lorenzo-López, Laura; Postolache, Teodor T. (Oxford University Press, 2023-11-06)
      [Abstract] Background: Persistent inflammation related to aging ("inflammaging") is exacerbated by chronic infections and contributes to frailty in older adults. We hypothesized associations between Toxoplasma gondii (T. ...